Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of iodothyronine deiodinases (DIO1, DIO3) genes are not associated with recurrent depressive disorder.

Pharmacological reports : PR - 1 Oct 2016

Gałecka Elżbieta, Talarowska Monika, Maes Michael, Su Kuan-Pin, Górski Paweł, Szemraj Janusz

Abstract excerpt

BACKGROUND: Depressive disorder is characterized by disturbances in the hypothalamic-pituitary-thyroid (HPT) axis and in the metabolism of thyroid hormones (TH). The evidence for changes in TH levels is observed in human sera and cerebrospinal fluid as well as in animal model studies. Iodothyronine deiodinases (DIOs) type 1, 2 and 3 (DIO1, DIO2, DIO3) are important enzymes for the synthesis and determination of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Depression
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Genetic Predisposition to Disease

Share to Iodide Peroxidase

Share to Polymorphism, Single Nucleotide

Share to Thyroid Hormones

Source

Identifiers

PMID: 27351946
DOI: 10.1016/j.pharep.2016.04.019

Genes

DIO3
DIO1
DIO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of iodothyronine deiodinases (DIO1, DIO3) genes are not associated with recurrent depressive disorder.PMID 27351946Read ↗

Polymorphisms in the type I deiodinase gene and frontal function in recurrent depressive disorder.Semantic proximity Read ↗

Association of the DIO2 gene single nucleotide polymorphisms with recurrent depressive disorder.Semantic proximity Read ↗

The relationship of deiodinase 1 genotype and thyroid function to lifetime history of major depression in three independent populations.Semantic proximity Read ↗

Genetics in endocrinology: genetic variation in deiodinases: a systematic review of potential clinical effects in humans.Semantic proximity Read ↗

The Thr92Ala polymorphism in the type 2 deiodinase gene is linked to depression in patients with COVID-19 after hospital discharge.Semantic proximity Read ↗

Genetic abnormalities in thyroid hormone deiodinases.Semantic proximity Read ↗

A common variation in deiodinase 1 gene DIO1 is associated with the relative levels of free thyroxine and triiodothyronine.Semantic proximity Read ↗

Deiodinases, organic anion transporter polypeptide polymorphisms and symptoms of anxiety and depression after ischemic stroke.Semantic proximity Read ↗

Preliminary evidence that a functional polymorphism in type 1 deiodinase is associated with enhanced potentiation of the antidepressant effect of sertraline by triiodothyronine.Semantic proximity Read ↗

Common variation in the DIO2 gene predicts baseline psychological well-being and response to combination thyroxine plus triiodothyronine therapy in hypothyroid patients.Semantic proximity Read ↗

Effect of DIO2 Gene Polymorphism on Thyroid Hormone Levels and Its Correlation with the Severity of Schizophrenia in a Pakistani Population.Semantic proximity Read ↗

Human Type 1 Iodothyronine Deiodinase (DIO1) Mutations Cause Abnormal Thyroid Hormone Metabolism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.