The Thr92Ala polymorphism in the type 2 deiodinase gene is linked to depression in patients with COVID-19 after hospital discharge.

doi:10.3389/fendo.2024.1366500

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The Thr92Ala polymorphism in the type 2 deiodinase gene is linked to depression in patients with COVID-19 after hospital discharge.

Frontiers in endocrinology - 1 Jan 2024

Beltrão Daniele Carvalhal de Almeida, Beltrão Fabyan Esberard de Lima, Carvalhal Giulia, Beltrão Fabyanna Lethicia de Lima, Brito Amanda da Silva, Silva Hatilla Dos Santos, Teixeira Helena Mariana Pitangueira, Rodrigues Juliana Lopes, de Figueiredo Camila Alexandrina Viana, Costa Ryan Dos Santos, Pordeus Liana Clebia De Morais, Vieira Giciane Carvalho, Ramos Helton Estrela

Abstract excerpt

Background: The Thr92Ala-DIO2 polymorphism has been associated with clinical outcomes in hospitalized patients with COVID-19 and neuropsychiatric diseases. This study examines the impact of the Thr92Ala-DIO2 polymorphism on neuropsychological symptoms, particularly depressive symptoms, in patients who have had moderate to severe SARS-CoV-2 infection and were later discharged. Methods: Our prospective cohort...

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Identifiers

PMID: 38911040
DOI: 10.3389/fendo.2024.1366500
PMCID: PMC11190161

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DIO2

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