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Article

The phenome-wide distribution of genetic variance.

The American naturalist - 1 Jul 2015

Blows Mark W, Allen Scott L, Collet Julie M, Chenoweth Stephen F, McGuigan Katrina

Abstract excerpt

A general observation emerging from estimates of additive genetic variance in sets of functionally or developmentally related traits is that much of the genetic variance is restricted to few trait combinations as a consequence of genetic covariance among traits. While this biased distribution of genetic variance among functionally related traits is now well documented, how it translates to the broader phenome and...

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Identifiers

PMID: 26098335
DOI: 10.1086/681645

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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