Article
The nature and extent of mutational pleiotropy in gene expression of male Drosophila serrata.
Genetics - 1 Mar 2014
McGuigan Katrina, Collet Julie M, McGraw Elizabeth A, Ye Yixin H, Allen Scott L, Chenoweth Stephen F, Blows Mark W
Abstract excerpt
The nature and extent of mutational pleiotropy remain largely unknown, despite the central role that pleiotropy plays in many areas of biology, including human disease, agricultural production, and evolution. Here, we investigate the variation in 11,604 gene expression traits among 41 mutation accumulation (MA) lines of Drosophila serrata. We first confirmed that these expression phenotypes were heritable,...
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