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Article

Systems genetics of complex traits in Drosophila melanogaster.

Nature genetics - 1 Mar 2009

Ayroles Julien F, Carbone Mary Anna, Stone Eric A, Jordan Katherine W, Lyman Richard F, Magwire Michael M, Rollmann Stephanie M, Duncan Laura H, Lawrence Faye, Anholt Robert R H, Mackay Trudy F C

Abstract excerpt

Determining the genetic architecture of complex traits is challenging because phenotypic variation arises from interactions between multiple, environmentally sensitive alleles. We quantified genome-wide transcript abundance and phenotypes for six ecologically relevant traits in D. melanogaster wild-derived inbred lines. We observed 10,096 genetically variable transcripts and high heritabilities for all organismal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19234471
DOI: 10.1038/ng.332
PMCID: PMC2752214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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