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Article

Genotype-phenotype mapping in a post-GWAS world.

Trends in genetics : TIG - 1 Sept 2012

Nuzhdin Sergey V, Friesen Maren L, McIntyre Lauren M

Abstract excerpt

Understanding how metabolic reactions, cell signaling, and developmental pathways translate the genome of an organism into its phenotype is a grand challenge in biology. Genome-wide association studies (GWAS) statistically connect genotypes to phenotypes, without any recourse to known molecular interactions, whereas a molecular biology approach directly ties gene function to phenotype through gene regulatory...

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PMID: 22818580
DOI: 10.1016/j.tig.2012.06.003
PMCID: PMC3476940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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