Article
The evolution of genetic architectures underlying quantitative traits.
Proceedings. Biological sciences - 22 Oct 2013
Rajon Etienne, Plotkin Joshua B
Abstract excerpt
In the classic view introduced by R. A. Fisher, a quantitative trait is encoded by many loci with small, additive effects. Recent advances in quantitative trait loci mapping have begun to elucidate the genetic architectures underlying vast numbers of phenotypes across diverse taxa, producing observations that sometimes contrast with Fisher's blueprint. Despite these considerable empirical efforts to map the...
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