Comparative transcriptional and translational analysis of heme oxygenase expression in response to sulfur mustard.

doi:10.3109/10799893.2015.1015735

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Article

Comparative transcriptional and translational analysis of heme oxygenase expression in response to sulfur mustard.

Journal of receptor and signal transduction research - 1 Jan 2015

Nourani Mohammad Reza, Mahmoodzadeh Hosseini Hamideh, Imani Fooladi Abbas Ali

Abstract excerpt

Sulfur mustard (SM) is a potent alkylating agent which reacts with nucleophilic groups on DNA, RNA and proteins. It is capable of inducing cellular toxicity and oxidative stress via production of reactive oxygen species (ROS) and reactive nitrogen species (RNS). The accumulation of high amounts of the reactive species causes harmful effects such as DNA damage, lipid peroxidation, protein oxidation, inflammation...

Topics

Animals
Dose-Response Relationship, Drug
Heme Oxygenase (Decyclizing)
Humans
Mustard Gas
Mutation
Protein Biosynthesis
Transcription, Genetic
Transcriptional Activation

Source

Open in PubMed

Identifiers

PMID: 26096165
DOI: 10.3109/10799893.2015.1015735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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