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Bacterial Responses to Glyoxal and Methylglyoxal: Reactive Electrophilic Species

17 Jan 2017

Abstract excerpt

Glyoxal (GO) and methylglyoxal (MG), belonging to α-oxoaldehydes, are produced by organisms from bacteria to humans by glucose oxidation, lipid peroxidation, and DNA oxidation. Since glyoxals contain two adjacent reactive carbonyl groups, they are referred to as reactive electrophilic species (RES), and are damaging to proteins and nucleotides. Therefore, glyoxals cause various diseases in humans, such as...

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PMID: 28106725
DOI: 10.3390/ijms18010169

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