Influence of the A118G Polymorphism of the OPRM1 Gene and Exon 3 VNTR Polymorphism of the DRD4 Gene on Cigarette Craving After Alcohol Administration.

doi:10.1093/ntr/ntv136

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Article

Influence of the A118G Polymorphism of the OPRM1 Gene and Exon 3 VNTR Polymorphism of the DRD4 Gene on Cigarette Craving After Alcohol Administration.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 May 2016

Lechner William V, Knopik Valerie S, McGeary John E, Spillane Nichea S, Tidey Jennifer W, McKee Sherry A, Metrik Jane, Leventhal Adam M, Rohsenow Damaris J, Kahler Christopher W

Abstract excerpt

INTRODUCTION: The current study examined whether the presence of the G allele of the A118G polymorphism of the OPRM1 gene (rs1799971) and the long allele of exon 3 VNTR polymorphism of the DRD4 gene moderate the effect of alcohol administration on urge to smoke. These polymorphisms have been associated with greater alcohol induced-urge to drink. Urge to drink and alcohol consumption increase urge to smoke....

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Identifiers

PMID: 26092968
DOI: 10.1093/ntr/ntv136
PMCID: PMC5896808

Genes

DRD4
OPRM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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