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Article

Differential neural response to alcohol priming and alcohol taste cues is associated with DRD4 VNTR and OPRM1 genotypes.

Alcoholism, clinical and experimental research - 1 Jul 2008

Filbey Francesca M, Ray Lara, Smolen Andrew, Claus Eric D, Audette Amy, Hutchison Kent E

Abstract excerpt

BACKGROUND: Studies suggest that polymorphisms in the D4 dopamine receptor (DRD4) and opioid receptor, mu 1 (OPRM1) genes are involved in differential response to the effects of alcohol and to alcohol cues. However, to date, the mechanisms that underlie these differences remain largely unknown. METHODS: Using functional magnetic resonance imaging, hemodynamic response in mesocorticolimbic structures after...

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Source

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Identifiers

PMID: 18540916
DOI: 10.1111/j.1530-0277.2008.00692.x
PMCID: PMC2856650

Genes

DRD4
OPRM1

Variants

Provenance

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