Article
Interactive effects of OPRM1 and DAT1 genetic variation on subjective responses to alcohol.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Ray Lara A, Bujarski Spencer, Squeglia Lindsay M, Ashenhurst James R, Anton Raymond F
Abstract excerpt
AIMS: Subjective response to alcohol represents a marker of alcoholism risk. The A118G single-nucleotide polymorphism (SNP) of the mu opioid receptor (OPRM1) gene has been associated with subjective response to alcohol. Recently, the dopamine transporter (DAT1) variable number of tandem repeat (VNTR; SLC6A3) has been found to interact with the OPRM1 A118G SNP in predicting neural and behavioral responses to...
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