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Article

Mutational landscape of nasopharyngeal carcinoma based on targeted next-generation sequencing: implications for predicting clinical outcomes.

Molecular medicine (Cambridge, Mass.) - 13 May 2022

Zhou Zihan, Li Peifeng, Zhang Xianbin, Xu Juan, Xu Jin, Yu Shui, Wang Dongqing, Dong Wei, Cao Xiujuan, Yan Hongjiang, Sun Mingping, Ding Xiuping, Xing Jun, Zhang Peng, Zhai Limin, Fan Tingyong, Tian Shiyu, Yang Xinhua, Hu Man

Abstract excerpt

BACKGROUND: The aim of this study was to draw a comprehensive mutational landscape of nasopharyngeal carcinoma (NPC) tumors and identify the prognostic factors for distant metastasis-free survival (DMFS). METHODS: A total of forty primary nonkeratinizing NPC patients underwent targeted next-generation sequencing of 450 cancer-relevant genes. Analysis of these sequencing and clinical data was performed...

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Identifiers

PMID: 35562651
DOI: 10.1186/s10020-022-00479-4
PMCID: PMC9107145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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