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Article

A novel genomic signature reclassifies an oral cancer subtype.

International journal of cancer - 15 Nov 2015

Samman Manar, Wood Henry M, Conway Caroline, Stead Lucy, Daly Catherine, Chalkley Rebecca, Berri Stefano, Senguven Burcu, Ross Lisa, Egan Philip, Chengot Preetha, Ong Thian K, Pentenero Monica, Gandolfo Sergio, Cassenti Adele, Cassoni Paola, Al Ajlan Abdulaziz, Samkari Alaa, Barrett William, MacLennan Kenneth, High Alec, Rabbitts Pamela

Abstract excerpt

Verrucous carcinoma of the oral cavity (OVC) is considered a subtype of classical oral squamous cell carcinoma (OSCC). Diagnosis is problematic, and additional biomarkers are needed to better stratify patients. To investigate their molecular signature, we performed low-coverage copy number (CN) sequencing on 57 OVC and exome and RNA sequencing on a subset of these and compared the data to the same OSCC...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26014678
DOI: 10.1002/ijc.29615

Genes

FAT1
NOTCH1
NOTCH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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