Candidate HLA genes for prediction of co-trimoxazole-induced severe cutaneous reactions.

doi:10.1097/FPC.0000000000000153

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Candidate HLA genes for prediction of co-trimoxazole-induced severe cutaneous reactions.

Pharmacogenetics and genomics - 1 Aug 2015

Kongpan Thachanan, Mahasirimongkol Surakameth, Konyoung Parinya, Kanjanawart Sirimas, Chumworathayi Pansu, Wichukchinda Nuanjun, Kidkeukarun Runglak, Preechakul Suphanlinee, Khunarkornsiri Usanee, Bamrungram Warawut, Supharatwattanakun Butsaban, Mootsikapun Piroon, Kwangsukstid Supanida, Denjanta Sukanda, Vannaprasaht Suda, Rungapiromnan Watcharee, Suwankesawong Wimon, Tassaneeyakul Wongwiwat, Tassaneeyakul Wichittra

Abstract excerpt

BACKGROUND: Co-trimoxazole is a sulfonamide-containing antibiotic that is effective in the treatment of several infections and for prophylaxis of Pneumocystis jiroveci pneumonia. This drug has been reported as a common culprit drug for the Stevens-Johnson syndrome (SJS) and for toxic epidermal necrolysis (TEN). Human leukocyte antigens (HLAs) play a key role in the immunopathogenesis of severe cutaneous reactions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Demography

Share to Drug-Induced Adverse Reactions

Share to Genetic Association Studies

Share to Genetic Predisposition to Disease

Share to HLA Antigens

Share to Stevens-Johnson Syndrome

Share to Trimethoprim, Sulfamethoxazole Drug Combination

Source

Open in PubMed

Identifiers

PMID: 26086150
DOI: 10.1097/FPC.0000000000000153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Candidate HLA genes for prediction of co-trimoxazole-induced severe cutaneous reactions.PMID 26086150Read ↗

Associations of HLA and drug-metabolizing enzyme genes in co-trimoxazole-induced severe cutaneous adverse reactions.Semantic proximity Read ↗

Genetic Association of Co-Trimoxazole-Induced Severe Cutaneous Adverse Reactions Is Phenotype-Specific: HLA Class I Genotypes and Haplotypes.Semantic proximity Read ↗

Whole genome sequencing identifies genetic variants associated with co-trimoxazole hypersensitivity in Asians.Semantic proximity Read ↗

HLA-B Alleles With Shared Peptide Binding Specificities Define Global Risk of Co-trimoxazole-Induced Severe Cutaneous Adverse Drug Reactions.Semantic proximity Read ↗

HLA-B Alleles with Shared Peptide Binding Specificities Define Global Risk of Cotrimoxazole-induced SCARSemantic proximity Read ↗

Genotypic and Phenotypic Characteristics of Co-Trimoxazole-Induced Cutaneous Adverse Reactions.Semantic proximity Read ↗

HLA Pharmacogenetic Markers of Drug Hypersensitivity in a Thai PopulationSemantic proximity Read ↗

Human Leukocyte Antigens and Sulfamethoxazole/Cotrimoxazole-Induced Severe Cutaneous Adverse Reactions: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Risk and association of HLA with oxcarbazepine-induced cutaneous adverse reactions in Asians.Semantic proximity Read ↗

Association between HLA alleles and beta-lactam antibiotics-related severe cutaneous adverse reactionsSemantic proximity Read ↗

Association of human antigen class I genes with cold medicine-related Stevens-Johnson syndrome with severe ocular complications in a Korean populationSemantic proximity Read ↗

Dapsone-induced severe cutaneous adverse drug reactions are strongly linked with HLA-B*13: 01 allele in the Thai population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.