Article
Congenital absence of corticospinal tract does not severely affect plastic changes of the developing postnatal spinal cord.
Neuroscience - 20 Aug 2015
Huang L, Xian Q, Shen N, Shi L, Qu Y, Zhou L
Abstract excerpt
The arrival and refinement of corticospinal afferents are likely to influence the maturation of the spinal cord and sensory-motor networks. To understand this better, we studied the revision of monosynaptic muscle afferents, the expression of activity-related genes, neurotrophins and their receptors in the cervical spinal cord from postnatal day (P) 0 to 21. We compared control and Celsr3|Emx1 mice, in which...
Topics
- Age Factors
- Animals
- Animals, Newborn
- Cadherins
- Gene Expression Regulation, Developmental
- Homeodomain Proteins
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mutation
- Nerve Growth Factors