Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alpha motoneurons are present in normal numbers but with reduced soma size in neurotrophin-3 knockout mice.

Neuroscience letters - 10 Sept 1999

Woolley A, Sheard P, Dodds K, Duxson M

Abstract excerpt

Neurotrophin-3 (NT-3) is essential for survival of proprioceptive and mechanoreceptor neurons, but its role in motoneuron development in vivo has seemed slight. Recent evidence however has suggested that NT-3 may be involved in motoneuron maturation. Here, we quantitatively assess the number and state of development of motoneurons within the lumbar lateral motor column (LLMC) of newborn NT-3 (-/-), (+/-) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Count
Share to Cell Size
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Motor Neurons

Share to Neurotrophin 3

Share to Spinal Cord

Source

Identifiers

PMID: 10507553
DOI: 10.1016/s0304-3940(99)00587-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alpha motoneurons are present in normal numbers but with reduced soma size in neurotrophin-3 knockout mice.PMID 10507553Read ↗

Effects of neurotrophin-3 gene mutation in the expression of neurocalcin.Semantic proximity Read ↗

Partial rescue of NT-3 null mutant phenotype by a PDGF-β regulated transgene.Semantic proximity Read ↗

Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements.Semantic proximity Read ↗

The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons.Semantic proximity Read ↗

Investigation of neuromuscular abnormalities in neurotrophin-3-deficient mice.Semantic proximity Read ↗

Congenital absence of corticospinal tract does not severely affect plastic changes of the developing postnatal spinal cord.Semantic proximity Read ↗

Severe peripheral sensory neuron loss and modest motor neuron reduction in mice with combined deficiency of brain-derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5.Semantic proximity Read ↗

Neurotrophin-3 is a survival factor in vivo for early mouse trigeminal neurons.Semantic proximity Read ↗

Thyroid hormone controls the development of connections between the spinal cord and limbs during Xenopus laevis metamorphosis.Semantic proximity Read ↗

Role of neurotrophins in mouse neuronal development.Semantic proximity Read ↗

Development of motoneuronal phenotype.Semantic proximity Read ↗

A novel phenotype for the dynein heavy chain mutation Loa: altered dendritic morphology, organelle density, and reduced numbers of trigeminal motoneurons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.