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Article

VAChT-Cre. Fast and VAChT-Cre.Slow: postnatal expression of Cre recombinase in somatomotor neurons with different onset.

Genesis (New York, N.Y. : 2000) - 1 Sept 2003

Misawa Hidemi, Nakata Kazuko, Toda Kyoko, Matsuura Junko, Oda Yoshio, Inoue Haruhisa, Tateno Minako, Takahashi Ryosuke

Abstract excerpt

The cholinergic gene locus (CGL) consists of the genes encoding the choline acetyltransferase (ChAT) and the vesicular acetylcholine transporter (VAChT). To establish a cholinergic-specific Cre-expressing mouse, we constructed a transgene expression vector (VAChT-Cre) with 11.3 kb human CGL in which a Cre-IRES-EGFP unit was inserted in the VAChT open reading frame. The activity of Cre, whose expression was driven...

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PMID: 14502577
DOI: 10.1002/gene.10224

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