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Article

A critical period for postnatal adaptive plasticity in a model of motor axon miswiring.

PloS one - 1 Jan 2015

Helmbrecht Michaela S, Soellner Heidi, Castiblanco-Urbina Maria A, Winzeck Stefan, Sundermeier Julia, Theis Fabian J, Fouad Karim, Huber Andrea B

Abstract excerpt

The correct wiring of neuronal circuits is of crucial importance for precise neuromuscular functionality. Therefore, guidance cues provide tight spatiotemporal control of axon growth and guidance. Mice lacking the guidance cue Semaphorin 3F (Sema3F) display very specific axon wiring deficits of motor neurons in the medial aspect of the lateral motor column (LMCm). While these deficits have been investigated...

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Identifiers

PMID: 25874621
DOI: 10.1371/journal.pone.0123643
PMCID: PMC4395312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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