Article
BRAF V600E and loss of heterozygosity assessment in benign oralneural tumours.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Sept 2015
Rodrigues Leonardo Nogueira, Correa GefterThiago Batista, Diniz Marina Gonçalves, Galvão Clarice Ferreira, Gomes Carolina Cavaliéri, Gomez Ricardo Santiago
Abstract excerpt
BACKGROUND: The purpose of this study was to evaluate loss of heterozygosity (LOH) and to assess BRAF V600E mutation in oral neurofibromas, palisaded encapsulated neuromas (PEN) and schwannomas. METHODS: Six oral neurofibroma, 5 PEN and 3 schwannoma samples were included in the study. LOH was assessed using polymorphic microsatellite markers at chromosome regions 3p (marker D3S1029), 9p (markers D9S171, D9S162,...
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