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Article

Molecular genetic analysis of the mechanism of tumorigenesis in acoustic neuroma.

Archives of otolaryngology--head & neck surgery - 1 Nov 1993

Irving R M, Moffat D A, Hardy D G, Barton D E, Xuereb J H, Maher E R

Abstract excerpt

OBJECTIVE: Acoustic neuroma, both familial and sporadic, is clinically and biologically a heterogeneous condition with a wide variation in age of presentation, length of history, and tumor growth rate. In an attempt to correlate this clinical diversity with the underlying molecular pathology, we have analyzed 43 paired blood-tumor DNA samples from patients with acoustic neuromas. DESIGN: Molecular genetic...

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Identifiers

PMID: 8217082
DOI: 10.1001/archotol.1993.01880230066011

Genes

VHL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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