Article
Molecular genetic analysis of the mechanism of tumorigenesis in acoustic neuroma.
Archives of otolaryngology--head & neck surgery - 1 Nov 1993
Irving R M, Moffat D A, Hardy D G, Barton D E, Xuereb J H, Maher E R
Abstract excerpt
OBJECTIVE: Acoustic neuroma, both familial and sporadic, is clinically and biologically a heterogeneous condition with a wide variation in age of presentation, length of history, and tumor growth rate. In an attempt to correlate this clinical diversity with the underlying molecular pathology, we...
Topics
- Adult
- Aged
- Aging
- Alleles
- Chromosome Deletion
- Chromosomes, Human, Pair 11
- Chromosomes, Human, Pair 17
- Chromosomes, Human, Pair 22
- Chromosomes, Human, Pair 3
- Chromosomes, Human, Pair 5
- Chronic Disease
- Female
- Genes, Tumor Suppressor
- Heterozygote
- Humans
- Male
- Middle Aged
- Neuroma, Acoustic