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Identification of major factors associated with failed clinical molecular oncology testing performed by next generation sequencing (NGS)

29 May 2015

Abstract excerpt

PURPOSE: DNA analysis by NGS has become important to direct the clinical care of cancer patients. However, NGS is not successful in all cases, and the factors responsible for test failures have not been systematically evaluated. MATERIALS AND METHODS: A series of 1528 solid and hematolymphoid tumor specimens was tested by an NGS comprehensive cancer panel during 2012-2014. DNA was extracted and 2×101 bp...

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PMID: 26071350
DOI: 10.1016/j.molonc.2015.05.004

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