Article
Minimizing Sample Failure Rates for Challenging Clinical Tumor Samples.
The Journal of molecular diagnostics : JMD - 1 May 2023
Fink J Lynn, Jaradi Binny, Stone Nathan, Anderson Lisa, Leo Paul J, Marshall Mhairi, Ellis Jonathan, Waring Paul M, O'Byrne Kenneth
Abstract excerpt
Identification of somatic variants in cancer by high-throughput sequencing has become common clinical practice, largely because many of these variants may be predictive biomarkers for targeted therapies. However, there can be high sample quality control (QC) failure rates for some tests that prevent the return of results. Stem-loop inhibition mediated amplification (SLIMamp) is a patented technology that has been...
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