Article

Impact of Pre-analytical Factors on the Success of Comprehensive Genomic Profiling in Gastrointestinal Tract Cancers

2025-08-21

Abstract excerpt

<title>Abstract</title> <p> Purpose Comprehensive genomic profiling (CGP) is an essential tool in precision oncology, but CGP success can be influenced by pre-analytical factors. This study aimed to evaluate the impact of pre-analytical factors on CGP success using formalin-fixed, paraffin-embedded (FFPE) tissue samples from patients with gastrointestinal (GI) tract cancers. Methods We retrospectively analyzed 2...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4e2cf5f5-932c-564c-bc3c-c3ab579e9e2e
DOI: 10.21203/rs.3.rs-7344606/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Impact of Pre-analytical Factors on the Success of Comprehensive Genomic Profiling in Gastrointestinal Tract CancersDOI 10.21203/rs.3.rs-7344606/v1Read

Impact of DNA integrity on the success rate of tissue‐based next‐generation sequencing: Lessons from nationwide cancer genome screening project SCRUM‐Japan GI‐SCREENSemantic proximity Read

The Japanese Society of Pathology Practical Guidelines on the handling of pathological tissue samples for cancer genomic medicineSemantic proximity Read

Investigating the feasibility of tumour molecular profiling in gastrointestinal malignancies in routine clinical practice.Semantic proximity Read

Genomic profiling and expanded use of targeted anticancer drugs in solid cancers with exhausted evidence-based treatment options: the PRECODE study protocolSemantic proximity Read

First-Line Genomic Profiling in Previously Untreated Advanced Solid Tumors for Identification of Targeted Therapy Opportunities.Semantic proximity Read

Study Protocol for a Prospective Self-Controlled Trial on Success in Meeting Comprehensive Genomic Profiling Analysis Criteria for Specimens Obtained by Endoscopic Ultrasound-Guided Tissue Acquisition Using a 19G Needle from Primary and Metastatic LesionsSemantic proximity Read

Clinical Utility of Genomic Profiling Tests in Patients with Advanced Gastrointestinal Cancers.Semantic proximity Read

The current state of molecular profiling in gastrointestinal malignancies.Semantic proximity Read

The success rates of clinical cancer next-generation sequencing based on pathologic diagnosis: Experience from a single academic laboratory.Semantic proximity Read

Clinical and diagnostic utility of genomic profiling for digestive cancers: real-world evidence from JapanSemantic proximity Read

Comprehensive genomic profiling for patients with chemotherapy‐naïve advanced cancerSemantic proximity Read

Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicineSemantic proximity Read