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Article

Challenges to the effectiveness of next-generation sequencing in formalin-fixed paraffin-embedded tumor samples for non-small cell lung cancer.

Annals of diagnostic pathology - 1 Apr 2024

da Silveira Corrêa Bruno, De-Paris Fernanda, Viola Guilherme Danielski, Andreis Tiago Finger, Rosset Clévia, Vianna Fernanda Sales Luiz, da Rosa Rivero Luis Fernando, de Oliveira Francine Hehn, Ashton-Prolla Patricia, de Souza Macedo Gabriel

Abstract excerpt

INTRODUCTION: Next-generation sequencing (NGS) of Formalin-Fixed and Paraffin-Embedded (FFPE) specimens is routine in precision oncology practice. However, results are not always conclusive, and it is important to identify which factors may influence FFPE tumor sequencing success. MATERIALS AND METHODS: Here, we evaluated the influence of pre-analytical factors on 705 samples of non-small cell lung cancer...

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Identifiers

PMID: 38150865
DOI: 10.1016/j.anndiagpath.2023.152249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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