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Article

A 3D human neural cell culture system for modeling Alzheimer's disease.

Nature protocols - 1 Jul 2015

Kim Young Hye, Choi Se Hoon, D'Avanzo Carla, Hebisch Matthias, Sliwinski Christopher, Bylykbashi Enjana, Washicosky Kevin J, Klee Justin B, Brüstle Oliver, Tanzi Rudolph E, Kim Doo Yeon

Abstract excerpt

Stem cell technologies have facilitated the development of human cellular disease models that can be used to study pathogenesis and test therapeutic candidates. These models hold promise for complex neurological diseases such as Alzheimer's disease (AD), because existing animal models have been unable to fully recapitulate all aspects of pathology. We recently reported the characterization of a novel 3D culture...

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Identifiers

PMID: 26068894
DOI: 10.1038/nprot.2015.065
PMCID: PMC4499058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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