Article
Distinct apical and basolateral mechanisms drive planar cell polarity-dependent convergent extension of the mouse neural plate.
Developmental cell - 14 Apr 2014
Williams Margot, Yen Weiwei, Lu Xiaowei, Sutherland Ann
Abstract excerpt
The mechanisms of tissue convergence and extension (CE) driving axial elongation in mammalian embryos, and in particular, the cellular behaviors underlying CE in the epithelial neural tissue, have not been identified. Here we show that mouse neural cells undergo mediolaterally biased cell intercalation and exhibit both apical boundary rearrangement and polarized basolateral protrusive activity. Planar...
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