Article
Fine mapping of hepatitis B virus pre-S deletion and its association with hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2012
Kao Jia-Horng, Liu Chun-Jen, Jow Guey-Mei, Chen Pei-Jer, Chen Ding-Shinn, Chen Bing-Fang
Abstract excerpt
BACKGROUND: Naturally occurring pre-S deletion mutants have been identified in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). AIMS: This study investigated whether specific deletions within the pre-S region were associated with HCC development. METHODS: The virologic characteristics of 56 HBV chronic carriers and 112 age-matched patients with HBV-related HCC were examined. RESULTS: The HCC...
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