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Article

miR-155 regulative network in FLT3 mutated acute myeloid leukemia.

Leukemia research - 1 Aug 2015

Salemi Domenico, Cammarata Giuseppe, Agueli Cecilia, Augugliaro Luigi, Corrado Chiara, Bica Maria Grazia, Raimondo Stefania, Marfia Anna, Randazzo Valentina, Dragotto Paola, Di Raimondo Francesco, Alessandro Riccardo, Fabbiano Francesco, Santoro Alessandra

Abstract excerpt

BACKGROUND: Acute myeloid leukemia (AML) represents a heterogeneous disorder with recurrent chromosomal alterations and molecular abnormalities. Among AML with normal karyotype (NK-AML) FLT3 activating mutation, internal tandem duplication (FLT3-ITD), is present in about 30% of patients, conferring unfavorable outcome. Our previous data demonstrated specific up-regulation of miR-155 in FLT3-ITD+ AML. miR-155 is...

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Source

Identifiers

PMID: 26055960
DOI: 10.1016/j.leukres.2015.04.017

Genes

FLT3
SPI1
JUN
RUNX1
JUNB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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