Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients.

doi:10.1200/JCO.2012.45.6228

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Article

Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Jun 2013

Marcucci Guido, Maharry Kati S, Metzeler Klaus H, Volinia Stefano, Wu Yue-Zhong, Mrózek Krzysztof, Nicolet Deedra, Kohlschmidt Jessica, Whitman Susan P, Mendler Jason H, Schwind Sebastian, Becker Heiko, Eisfeld Ann-Kathrin, Carroll Andrew J, Powell Bayard L, Kolitz Jonathan E, Garzon Ramiro, Caligiuri Michael A, Stone Richard M, Bloomfield Clara D

Abstract excerpt

PURPOSE: To evaluate the impact of miR-155 on the outcome of adults with cytogenetically normal (CN) acute myeloid leukemia (AML) in the context of other clinical and molecular prognosticators and to gain insight into the leukemogenic role of this microRNA. PATIENTS AND METHODS: We evaluated 363...

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PMID: 23650424
DOI: 10.1200/JCO.2012.45.6228
PMCID: PMC3731981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23650424-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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