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Article

MicroRNA-155 as an inducer of apoptosis and cell differentiation in Acute Myeloid Leukaemia.

Molecular cancer - 5 Apr 2014

Palma Catalina A, Al Sheikha Dima, Lim Teck Khai, Bryant Adam, Vu Thi Thanh, Jayaswal Vivek, Ma David D F

Abstract excerpt

BACKGROUND: Acute myeloid leukaemia (AML) is characterised by the halt in maturation of myeloid progenitor cells, combined with uncontrolled proliferation and abnormal survival, leading to the accumulation of immature blasts. In many subtypes of AML the underlying causative genetic insults are not fully described. MicroRNAs are known to be dysregulated during oncogenesis. Overexpression of miR-155 is associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24708856
DOI: 10.1186/1476-4598-13-79
PMCID: PMC4021368

Genes

FLT3
CTNNB1
FOS
JARID2
MEIS1
TRIB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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