Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential expression of specific microRNA and their targets in acute myeloid leukemia.

American journal of hematology - 1 May 2010

Cammarata Giuseppe, Augugliaro Luigi, Salemi Domenico, Agueli Cecilia, La Rosa Maria, Dagnino Lea, Civiletto Gabriele, Messana Francesca, Marfia Anna, Bica Maria Grazia, Cascio Lucia, Floridia Pietro Michele, Mineo Angelo M, Russo Mario, Fabbiano Francesco, Santoro Alessandra

Abstract excerpt

Acute myeloid leukemia (AML) the most common acute leukemia in adults is characterized by various cytogenetic and molecular abnormalities. However, the genetic etiology of the disease is not yet fully understood. MicroRNAs (miRNA) are small noncoding RNAs which regulate the expression of target mRNAs both at transcriptional and translational level. In recent years, miRNAs have been identified as a novel mechanism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Core Binding Factors
Share to Down-Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to fms-Like Tyrosine Kinase 3

Share to Gene Expression Regulation, Neoplastic

Share to Leukemia, Myeloid, Acute

Share to MicroRNAs

Share to Nucleophosmin

Share to Up-Regulation

Source

Identifiers

PMID: 20425795
DOI: 10.1002/ajh.21667

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential expression of specific microRNA and their targets in acute myeloid leukemia.PMID 20425795Read ↗

MicroRNAs as New Biomarkers for Diagnosis and Prognosis, and as Potential Therapeutic Targets in Acute Myeloid LeukemiaSemantic proximity Read ↗

MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemiaSemantic proximity Read ↗

MicroRNA ‐based therapies: Revolutionizing the treatment of acute myeloid leukemiaSemantic proximity Read ↗

MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status.Semantic proximity Read ↗

MicroRNA expression in acute myeloid leukemia.Semantic proximity Read ↗

Pathogenic microRNAâ€™s in myeloid malignanciesSemantic proximity Read ↗

MicroRNA-155 expression and function in AML: An evolving paradigm.Semantic proximity Read ↗

Differentially expressed miRNAs in cytogenetic and molecular subtypes of pediatric acute myeloid leukemiaSemantic proximity Read ↗

Functional implications of microRNAs in acute myeloid leukemia by integrating microRNA and messenger RNA expression profilingSemantic proximity Read ↗

Identification of let-7a-2-3p or/and miR-188-5p as Prognostic Biomarkers in Cytogenetically Normal Acute Myeloid LeukemiaSemantic proximity Read ↗

Deregulation of miR-1, miR486, and let-7a in cytogenetically normal acute myeloid leukemia: association with NPM1 and FLT3 mutation and clinical characteristics.Semantic proximity Read ↗

Diverse functions of long noncoding RNAs in acute myeloid leukemia: emerging roles in pathophysiology, prognosis, and treatment resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.