Article

miR-155 expression and function in leukemic stem cells

2024-03-04

Abstract excerpt

<h4>ABSTRACT</h4> It has been reported that elevated levels of miR-155 have been reported in patients with Acute Myeloid Leukemia (AML) bearing FLT3 -ITD mutations and is independent of FLT3 -ITD signaling. However, it is unclear how miR-155 is expressed in leukemic stem cells (LCS) and whether miR-155 has any role regulating LSC functions. In this manuscript, we defined the expression of miR-155 in clearly def...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3d598384-e269-5d31-a708-1e6e332ec07e
DOI: 10.1101/2024.02.29.582835

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

miR-155 expression and function in leukemic stem cellsDOI 10.1101/2024.02.29.582835Read

MicroRNA-155 expression and function in AML: An evolving paradigm.Semantic proximity Read

The role of microRNAs in normal and malignant hematopoiesisSemantic proximity Read

MiR‐155 targets TP53INP1 to regulate liver cancer stem cell acquisition and self‐renewalSemantic proximity Read

miR-155 promotes FLT3-ITD-induced myeloproliferative disease through inhibition of the interferon response.Semantic proximity Read

MiR-155/miR-150 network regulates progression through the disease phases of chronic lymphocytic leukemiaSemantic proximity Read

Direct Binding of miR-155 to FLT3 Regulates Key Cellular Functions in Acute Myeloid LeukemiaSemantic proximity Read

MicroRNA-155 as an inducer of apoptosis and cell differentiation in Acute Myeloid Leukaemia.Semantic proximity Read

[Expression and Prognostic Value of MiR-155 in Patients with Chronic Lymphocytic Leukemia].Semantic proximity Read

MicroRNA-155 promotes G-CSF-induced mobilization of murine hematopoietic stem and progenitor cells via propagation of CXCL12 signaling.Semantic proximity Read

miRNA‐155 and miRNA‐181a as prognostic biomarkers for pediatric acute lymphoblastic leukemiaSemantic proximity Read

Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients.Semantic proximity Read

MicroRNAs in normal and malignant hematopoiesisSemantic proximity Read