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Article

Psychiatric Polygenic Risk Scores Across Youth With Bipolar Disorder, Youth at High Risk for Bipolar Disorder, and Controls.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Nov 2024

Jiang Xinyue, Zai Clement C, Dimick Mikaela K, Kennedy James L, Young L Trevor, Birmaher Boris, Goldstein Benjamin I

Abstract excerpt

OBJECTIVE: There is a pronounced gap in knowledge regarding polygenic underpinnings of youth bipolar disorder (BD). This study aimed to compare polygenic risk scores (PRSs) in youth with BD, youth at high clinical and/or familial risk for BD (HR), and controls. METHOD: Participants were 344 youths of European ancestry (13-20 years old), including 136 youths with BD, 121 HR youths, and 87 controls. PRSs for BD,...

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Source

Identifiers

PMID: 38340895
DOI: 10.1016/j.jaac.2023.12.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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