Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Discriminating bipolar depression from major depressive disorder with polygenic risk scores.

Psychological medicine - 1 Jul 2021

Liebers David T, Pirooznia Mehdi, Ganna Andrea, Goes Fernando S

Abstract excerpt

BACKGROUND: Although accurate differentiation between bipolar disorder (BD) and unipolar major depressive disorder (MDD) has important prognostic and therapeutic implications, the distinction is often challenging based on clinical grounds alone. In this study, we tested whether psychiatric polygenic risk scores (PRSs) improve clinically based classification models of BD v. MDD diagnosis. METHODS: Our sample...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Depressive Disorder, Major
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Multifactorial Inheritance

Share to Risk Factors

Share to Schizophrenia

Source

Identifiers

PMID: 32063240
DOI: 10.1017/S003329172000015X

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Discriminating bipolar depression from major depressive disorder with polygenic risk scores.PMID 32063240Read ↗

The use of polygenic risk scores to identify phenotypes associated with genetic risk of bipolar disorder and depression: A systematic review.Semantic proximity Read ↗

Polygenic risk scores in bipolar disorder subgroups.Semantic proximity Read ↗

Dissecting clinical heterogeneity of bipolar disorder using multiple polygenic risk scoresSemantic proximity Read ↗

Analysis of genetic differences between psychiatric disorders: exploring pathways and cell types/tissues involved and ability to differentiate the disorders by polygenic scores.Semantic proximity Read ↗

Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia With Risk for Depression in the Danish PopulationSemantic proximity Read ↗

Advancing the Prediction of Factors associated with Bipolar Disorder Risk: Utilizing Early Recognition Tools and Polygenic Risk ScoresSemantic proximity Read ↗

Identifying genetic differences between bipolar disorder and major depression through multiple GWASSemantic proximity Read ↗

Molecular genetic overlap in bipolar disorder, schizophrenia, and major depressive disorder.Semantic proximity Read ↗

Key subphenotypes of bipolar disorder are differentially associated with polygenic liabilities for bipolar disorder, schizophrenia, and major depressive disorder.Semantic proximity Read ↗

Specificity of polygenic signatures across symptom dimensions in bipolar disorder: an analysis of UK Bipolar Disorder Research Network data.Semantic proximity Read ↗

Polygenic Risk Scores Derived From Varying Definitions of Depression and Risk of Depression.Semantic proximity Read ↗

Polygenic Risk Scores for Bipolar Disorder: Progress and PerspectivesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.