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Article

CREB1 Genotype Modulates Adaptive Reward-Based Decisions in Humans.

Cerebral cortex (New York, N.Y. : 1991) - 1 Jul 2016

Wolf Claudia, Mohr Holger, Diekhof Esther K, Vieker Henning, Goya-Maldonado Roberto, Trost Sarah, Krämer Bernd, Keil Maria, Binder Elisabeth B, Gruber Oliver

Abstract excerpt

Cyclic AMP response element-binding protein (CREB) contributes to adaptation of mesocorticolimbic networks by modulating activity-regulated transcription and plasticity in neurons. Activity or expression changes of CREB in the nucleus accumbens (NAc) and orbital frontal cortex (OFC) interact with behavioral changes during reward-motivated learning. However, these findings from animal models have not been...

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Identifiers

PMID: 26045569
DOI: 10.1093/cercor/bhv104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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