Article
BDNF Val66Met polymorphism tunes frontolimbic circuitry during affective contextual learning.
NeuroImage - 15 Nov 2017
Jabbi Mbemba, Cropp Brett, Nash Tiffany, Kohn Philip, Kippenhan J Shane, Masdeu Joseph C, Mattay Raghav, Kolachana Bhaskar, Berman Karen F
Abstract excerpt
Adaptive learning impairments are common in cognitive and behavioral disorders, but the neurogenetic mechanisms supporting human affective learning are poorly understood. We designed a higher-order contextual learning task in which healthy participants genotyped for the Val66Met polymorphism of the brain derived neurotropic factor gene (BDNF) were required to choose the member of a picture pair most congruent...
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