Back to search

Article

Bivalent habenula modulation of human monoaminergic midbrain and cortical pathways

2025-12-27

Abstract excerpt

The habenula is implicated in signaling negative reward prediction errors (RPE), yet direct causal evidence demonstrating its influence on downstream human brain circuits is limited. Using ultra-high field (7T) fMRI and dynamic causal modelling across two negative RPE-inducing experimental tasks, we characterize habenula-directed connectivity with monoaminergic midbrain and cortical pathways in healthy adults. Neg...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d8336bb1-cc1e-537d-996c-6ed5e0dae67a
DOI
10.64898/2025.12.26.696619
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Bivalent habenula modulation of human monoaminergic midbrain and cortical pathwaysDOI 10.64898/2025.12.26.696619
Hierarchical prediction errors in midbrain and septum during social learning.Semantic proximity
Cortical and thalamic influences on striatal involvement in instructed, serial reversal learning; implications for the organisation of flexible behaviourSemantic proximity
Placebo treatment entails resource-dependent downregulation of negative inputsSemantic proximity
Translational Evidence for Habenula’s Role in Human Addiction: A Scoping ReviewSemantic proximity
Music-to My Brain: Modulation of Reward System Activity via Musical NeurofeedbackSemantic proximity
ACTIVITY IN HUMAN DORSAL RAPHE NUCLEUS SIGNALS CHANGES IN BEHAVIOURAL POLICYSemantic proximity
Activity patterns of serotonin neurons underlying cognitive flexibilitySemantic proximity
NEUROSCIENCE. A tree of the human brain.Semantic proximity
Valence-partitioned learning signals drive choice behavior and phenomenal subjective experience in humansSemantic proximity
Effects of exogenous oxytocin on human brain function are regulated by oxytocin gene expression: a meta-analysis of 20 years of oxytocin neuroimaging and transcriptomic analysesSemantic proximity
A causal test of affect processing bias in response to affect regulationSemantic proximity
Neuromodulatory systems partially account for the topography of cortical networks of learning under uncertaintySemantic proximity
Select a neighboring publication to make it the new centre.