Article
Genetic determinants of quantitative traits associated with cardiovascular disease risk.
Mutation research - 1 Aug 2015
Smolková Božena, Bonassi Stefano, Buociková Verona, Dušinská Mária, Horská Alexandra, Kuba Daniel, Džupinková Zuzana, Rašlová Katarína, Gašparovič Juraj, Slíž Ivan, Ceppi Marcello, Vohnout Branislav, Wsólová Ladislava, Volkovová Katarína
Abstract excerpt
Established risk factors for cardiovascular diseases (CVD) may be moderated by genetic variants. In 2403 unrelated individuals from general practice (mean age 40.5 years), we evaluated the influence of 15 variants in 12 candidate genes on quantitative traits (QT) associated with CVD (body mass index, abdominal obesity, glucose, serum lipids, and blood pressure). Prior to multiple testing correction, univariate...
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