Article
Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
Nature genetics - 1 Feb 2008
Willer Cristen J, Sanna Serena, Jackson Anne U, Scuteri Angelo, Bonnycastle Lori L, Clarke Robert, Heath Simon C, Timpson Nicholas J, Najjar Samer S, Stringham Heather M, Strait James, Duren William L, Maschio Andrea, Busonero Fabio, Mulas Antonella, Albai Giuseppe, Swift Amy J, Morken Mario A, Narisu Narisu, Bennett Derrick, Parish Sarah, Shen Haiqing, Galan Pilar, Meneton Pierre, Hercberg Serge, Zelenika Diana, Chen Wei-Min, Li Yun, Scott Laura J, Scheet Paul A, Sundvall Jouko, Watanabe Richard M, Nagaraja Ramaiah, Ebrahim Shah, Lawlor Debbie A, Ben-Shlomo Yoav, Davey-Smith George, Shuldiner Alan R, Collins Rory, Bergman Richard N, Uda Manuela, Tuomilehto Jaakko, Cao Antonio, Collins Francis S, Lakatta Edward, Lathrop G Mark, Boehnke Michael, Schlessinger David, Mohlke Karen L, Abecasis Gonçalo R
Abstract excerpt
To identify genetic variants influencing plasma lipid concentrations, we first used genotype imputation and meta-analysis to combine three genome-wide scans totaling 8,816 individuals and comprising 6,068 individuals specific to our study (1,874 individuals from the FUSION study of type 2 diabetes and 4,184 individuals from the SardiNIA study of aging-associated variables) and 2,758 individuals from the Diabetes...
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