Article
Genetic variants in lipid metabolism are independently associated with multiple features of the metabolic syndrome.
Lipids in health and disease - 18 Jul 2011
Povel Cécile M, Boer Jolanda M A, Imholz Sandra, Dollé Martijn E T, Feskens Edith J M
Abstract excerpt
BACKGROUND: Our objective was to find single nucleotide polymorphisms (SNPs), within transcriptional pathways of glucose and lipid metabolism, which are related to multiple features of the metabolic syndrome (MetS). METHODS: 373 SNPs were measured in 3575 subjects of the Doetinchem cohort. Prevalence of MetS features, i.e. hyperglycemia, abdominal obesity, decreased HDL-cholesterol levels and hypertension, were...
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