Article
The Chromatin Remodeling Protein Bptf Promotes Posterior Neuroectodermal Fate by Enhancing Smad2-Activated wnt8a Expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Jun 2015
Ma Yuanqing, Liu Xiuli, Liu Zhaoting, Wei Shi, Shang Hanqiao, Xue Yu, Cao Yu, Meng Anming, Wang Qiang
Abstract excerpt
During vertebrate embryogenesis, the neuroectoderm is induced from dorsal ectoderm and then partitioned into anterior and posterior neuroectodermal domains by posteriorizing signals, such as Wnt and fibroblast growth factor. However, little is known about epigenetic regulation of posteriorizing gene expression. Here, we report a requirement of the chromatin remodeling protein Bptf for neuroectodermal...
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