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Article

The role and regulation of GDF11 in Smad2 activation during tailbud formation in the Xenopus embryo.

Mechanisms of development - 1 Jan 2000

Ho Diana M, Yeo Chang-Yeol, Whitman Malcolm

Abstract excerpt

A key role for phosphorylation of Smad2 by TGFβ superfamily ligands in the axial patterning of early embryos is well established. The regulation and role of Smad2 signaling in post-neurula embryonic patterning, however, is less well understood. While a variety of TGFβ superfamily ligands are implicated in various stages of anterior-posterior patterning, the ligand GDF11 has been shown to have a particular role in...

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Source

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Identifiers

PMID: 20807570
DOI: 10.1016/j.mod.2010.08.004
PMCID: PMC4136463

Genes

GDF11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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