Article
Analysis of Wnt8 for neural posteriorizing factor by identifying Frizzled 8c and Frizzled 9 as functional receptors for Wnt8.
Mechanisms of development - 1 Apr 2003
Momoi Akihiro, Yoda Hiroki, Steinbeisser Herbert, Fagotto Francois, Kondoh Hisato, Kudo Akira, Driever Wolfgang, Furutani-Seiki Makoto
Abstract excerpt
The dorsal ectoderm of vertebrate gastrula is first specified into anterior fate by an activation signal and posteriorized by a graded transforming signal, leading to the formation of forebrain, midbrain, hindbrain and spinal cord along the anteroposterior (A-P) axis. Transplanted non-axial mesod...
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