Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pbx genes are required in Xenopus lens development.

The International journal of developmental biology - 1 Sept 2004

Morgan Richard, Sohal Jastinder, Paleja Mita, Pettengell Ruth

Abstract excerpt

Development of the vertebrate eye is dependent on multiple tissue interactions and distinct sets of transcription factors and signalling molecules. The latter are thought to be FGF8 and BMP4, proteins secreted from the neural plate to induce lens formation in the overlying ectoderm. Here we show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Morphogenetic Protein 4
Share to Bone Morphogenetic Proteins
Share to Ectoderm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factor 8

Share to Fibroblast Growth Factors

Share to Lens, Crystalline

Share to Neural Crest

Share to Xenopus Proteins

Source

Identifiers

PMID: 15470634
DOI: 10.1387/ijdb.041887rm

Genes

FGF8
BMP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15470634-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pbx genes are required in Xenopus lens development.PMID 15470634Read ↗

Developmental patterning genes and their conserved functions: from model organisms to humans.Semantic proximity Read ↗

Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression.Semantic proximity Read ↗

dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activity.Semantic proximity Read ↗

Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation.Semantic proximity Read ↗

Prdm1 acts downstream of a sequential RA, Wnt and Fgf signaling cascade during zebrafish forelimb induction.Semantic proximity Read ↗

Genetic aspects of embryonic eye development in vertebrates.Semantic proximity Read ↗

BMP signaling protects telencephalic fate by repressing eye identity and its Cxcr4-dependent morphogenesis.Semantic proximity Read ↗

XBP1 forms a regulatory loop with BMP-4 and suppresses mesodermal and neural differentiation in Xenopus embryos.Semantic proximity Read ↗

FGF8, Wnt8 and Myf5 are target genes of Tbx6 during anteroposterior specification in Xenopus embryo.Semantic proximity Read ↗

Transdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signallingSemantic proximity Read ↗

Ptf1a/Rbpj complex inhibits ganglion cell fate and drives the specification of all horizontal cell subtypes in the chick retinaSemantic proximity Read ↗

The Chromatin Remodeling Protein Bptf Promotes Posterior Neuroectodermal Fate by Enhancing Smad2-Activated wnt8a Expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.