Article
Inactivation of the T6SS inner membrane protein DotU results in severe attenuation and decreased pathogenicity of Aeromonas veronii TH0426.
BMC microbiology - 3 Apr 2020
Song Haichao, Kang Yuanhuan, Qian Aidong, Shan Xiaofeng, Li Ying, Zhang Lei, Zhang Haipeng, Sun Wuwen
Abstract excerpt
BACKGROUND: The inner membrane protein DotU of Aeromonas veronii is an important component of the minimal core conserved membrane proteome required for the formation of an envelope-transmembrane complex. This protein functions in a type VI secretion system (T6SS), and the role of this T6SS during the pathogenic process has not been clearly described. RESULTS: A recombinant A. veronii with a partial disruption of...
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