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Article

Estimation of Genetic Relationships Between Individuals Across Cohorts and Platforms: Application to Childhood Height.

Behavior genetics - 1 Sept 2015

Fedko Iryna O, Hottenga Jouke-Jan, Medina-Gomez Carolina, Pappa Irene, van Beijsterveldt Catharina E M, Ehli Erik A, Davies Gareth E, Rivadeneira Fernando, Tiemeier Henning, Swertz Morris A, Middeldorp Christel M, Bartels Meike, Boomsma Dorret I

Abstract excerpt

Combining genotype data across cohorts increases power to estimate the heritability due to common single nucleotide polymorphisms (SNPs), based on analyzing a Genetic Relationship Matrix (GRM). However, the combination of SNP data across multiple cohorts may lead to stratification, when for examp...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 26036992
DOI: 10.1007/s10519-015-9725-7
PMCID: PMC4561077

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26036992-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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