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Article

Estimation of Genetic Relationships Between Individuals Across Cohorts and Platforms: Application to Childhood Height.

Behavior genetics - 1 Sept 2015

Fedko Iryna O, Hottenga Jouke-Jan, Medina-Gomez Carolina, Pappa Irene, van Beijsterveldt Catharina E M, Ehli Erik A, Davies Gareth E, Rivadeneira Fernando, Tiemeier Henning, Swertz Morris A, Middeldorp Christel M, Bartels Meike, Boomsma Dorret I

Abstract excerpt

Combining genotype data across cohorts increases power to estimate the heritability due to common single nucleotide polymorphisms (SNPs), based on analyzing a Genetic Relationship Matrix (GRM). However, the combination of SNP data across multiple cohorts may lead to stratification, when for example, different genotyping platforms are used. In the current study, we address issues of combining SNP data from...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26036992
DOI: 10.1007/s10519-015-9725-7
PMCID: PMC4561077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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