Article
Estimating narrow-sense heritability using family data from admixed populations.
Heredity - 1 Jun 2020
Athanasiadis Georgios, Speed Doug, Andersen Mette K, Appel Emil V R, Grarup Niels, Brandslund Ivan, Jørgensen Marit Eika, Larsen Christina Viskum Lytken, Bjerregaard Peter, Hansen Torben, Albrechtsen Anders
Abstract excerpt
Estimating total narrow-sense heritability in admixed populations remains an open question. In this work, we used extensive simulations to evaluate existing linear mixed-model frameworks for estimating total narrow-sense heritability in two population-based cohorts from Greenland, and compared the results with data from unadmixed individuals from Denmark. When our analysis focused on Greenlandic sib pairs, and...
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