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Article

Evaluation and application of summary statistic imputation to discover new height-associated loci.

PLoS genetics - 1 May 2018

Rüeger Sina, McDaid Aaron, Kutalik Zoltán

Abstract excerpt

As most of the heritability of complex traits is attributed to common and low frequency genetic variants, imputing them by combining genotyping chips and large sequenced reference panels is the most cost-effective approach to discover the genetic basis of these traits. Association summary statistics from genome-wide meta-analyses are available for hundreds of traits. Updating these to ever-increasing reference...

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Identifiers

PMID: 29782485
DOI: 10.1371/journal.pgen.1007371
PMCID: PMC5983877

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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