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Article

From Galton to GWAS: quantitative genetics of human height.

Genetics research - 1 Dec 2010

Visscher Peter M, McEvoy Brian, Yang Jian

Abstract excerpt

Height has been studied in human genetics since the late 1800s. We review what we have learned about the genetic architecture of this trait from the resemblance between relatives and from genetic marker data. All empirical evidence points towards height being highly polygenic, with many loci contributing to variation in the population and most effect sizes appear to be small. Nevertheless, combining new genetic...

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PMID: 21429269
DOI: 10.1017/S0016672310000571

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